Basic Information
ID: ALA4327005
Type: Binding
Description: Inhibition of JNK in human THP1-Blue cells assessed as reduction in LPS-induced NFkappaB/AP1 activation up to 50 uM preincubated for 30 mins followed by LPS-stimulation and measured after 24 hrs by quanti-blue staining based alkaline phosphatase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4327005
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.24 | 3.86 | 3.86 |
| 246.27 | 3.15 | 3.15 |
| 246.27 | 3.15 | 3.15 |
| 233.23 | 2.24 | 2.24 |
| 260.30 | 3.46 | 3.46 |
| 276.25 | 2.54 | 2.54 |
| 276.30 | 3.24 | 3.24 |
| 266.69 | 3.49 | 3.49 |
| 233.23 | 2.24 | 2.24 |
| 301.13 | 4.15 | 4.15 |
| 277.24 | 2.75 | 2.75 |