Basic Information
ID: ALA4327018
Type: Binding
Description: Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followed by substrate addition and measured after 30 mins by LC/MS/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4327018
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.26 | 3.10 | 3.10 |
| 329.36 | 1.22 | 1.22 |
| 376.39 | 1.00 | 1.00 |
| 396.49 | 2.87 | 2.87 |
| 419.48 | 2.75 | 2.75 |
| 328.37 | 1.10 | 1.10 |
| 314.35 | 0.71 | 0.71 |
| 392.42 | 1.64 | 1.64 |
| 385.46 | 2.35 | 2.35 |
| 434.50 | 2.68 | 2.68 |
| 314.35 | 0.71 | 0.71 |
| 406.44 | 2.03 | 2.03 |
| 404.47 | 2.56 | 2.56 |
| 376.42 | 2.04 | 2.04 |
| 373.41 | 0.69 | 0.69 |
| 328.41 | 2.50 | 2.50 |