Basic Information
ID: ALA4327284
Type: Binding
Description: Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate measured after 1 hr in presence of Adomet by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4327284
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 528.70 | 6.19 | 6.19 |
| 545.66 | 5.53 | 5.53 |
| 508.67 | 5.04 | 5.04 |
| 485.61 | 5.51 | 5.51 |
| 506.70 | 5.47 | 5.47 |
| 492.67 | 5.08 | 5.08 |
| 614.79 | 6.62 | 6.62 |
| 524.67 | 4.75 | 4.75 |
| 511.60 | 5.21 | 5.21 |
| 508.67 | 5.04 | 5.04 |
| 538.70 | 5.05 | 5.05 |