Basic Information
ID: ALA4327286
Type: Binding
Description: Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) at 10 uM using 5'-biotinylated/3'-FAM-oligonucleotide as substrate measured after 1 hr in presence of Adomet by fluorescence assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA (cytosine-5)-methyltransferase 3A(ALA1992)
Document: ALA4325862
Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) at 10 uM using 5'-biotinylated/3'-FAM-oligonucleotide as substrate measured after 1 hr in presence of Adomet by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4327286
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 610.76 | 7.22 | 7.22 |
| 584.77 | 6.61 | 6.61 |