Basic Information
ID: ALA4327374
Type: Binding
Description: Competitive inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in HEK293F cells pretreated for 15 mins followed by varying peptide substrate and and fixed [3H]-SAM addition measured after 60 mins by scintillation proximity assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Protein arginine N-methyltransferase 5(ALA1795116)
Document: ALA4325864
Competitive inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in HEK293F cells pretreated for 15 mins followed by varying peptide substrate and and fixed [3H]-SAM addition measured after 60 mins by scintillation proximity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4327374
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.28 | 3.71 | 3.71 |