Assay Report Card

Basic Information

ID: ALA4327374

Type: Binding

Description: Competitive inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in HEK293F cells pretreated for 15 mins followed by varying peptide substrate and and fixed [3H]-SAM addition measured after 60 mins by scintillation proximity assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
384.283.713.71