Basic Information
ID: ALA4327489
Type: Binding
Description: Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as potentiation of doxorubicin-induced cytotoxicity preincubated for 24 hrs followed by doxorubicin addition measured after 72 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDCK
Target: P-glycoprotein 1(ALA4302)
Document: ALA4325869
Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as potentiation of doxorubicin-induced cytotoxicity preincubated for 24 hrs followed by doxorubicin addition measured after 72 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4327489
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.61 | 5.61 | 5.61 |
| 516.43 | 5.49 | 5.49 |
| 391.51 | 5.02 | 5.02 |
| 499.61 | 6.08 | 6.08 |
| 513.63 | 6.39 | 6.39 |
| 451.56 | 5.03 | 5.03 |