Basic Information
ID: ALA4328666
Type: Binding
Description: Inhibition of human GST-tagged catalytic ROCK1 expressed in baculovirus system using STK S2 peptide substrate and and 33P-ATP after 60 mins by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4328666
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 288.35 | 3.68 | 3.68 |
| 318.38 | 3.69 | 3.69 |
| 444.58 | 4.42 | 4.42 |
| 389.50 | 4.01 | 4.01 |
| 449.53 | 4.09 | 4.09 |
| 346.43 | 4.56 | 4.56 |
| 375.47 | 4.68 | 4.68 |
| 391.47 | 3.65 | 3.65 |
| 348.40 | 3.70 | 3.70 |
| 332.40 | 4.25 | 4.25 |
| 366.85 | 4.90 | 4.90 |
| 332.40 | 4.08 | 4.08 |
| 385.51 | 4.71 | 4.71 |
| 350.39 | 4.39 | 4.39 |
| 333.39 | 3.64 | 3.64 |
| 360.41 | 3.84 | 3.84 |
| 445.57 | 3.82 | 3.82 |
| 362.43 | 3.61 | 3.61 |
| 360.46 | 5.03 | 5.03 |
| 475.61 | 6.02 | 6.02 |
| 350.39 | 4.39 | 4.39 |
| 347.42 | 3.83 | 3.83 |
| 372.35 | 4.58 | 4.58 |
| 346.43 | 4.47 | 4.47 |
| 421.49 | 4.98 | 4.98 |
| 346.39 | 3.45 | 3.45 |
| 304.35 | 3.38 | 3.38 |
| 360.46 | 4.87 | 4.87 |
| 431.54 | 3.43 | 3.43 |
| 431.54 | 3.43 | 3.43 |
| 404.51 | 4.01 | 4.01 |
| 418.54 | 4.40 | 4.40 |
| 401.51 | 5.07 | 5.07 |
| 445.57 | 3.82 | 3.82 |
| 419.53 | 4.43 | 4.43 |
| 417.51 | 3.39 | 3.39 |
| 390.49 | 3.62 | 3.62 |
| 332.40 | 4.25 | 4.25 |
| 408.47 | 4.53 | 4.53 |
| 415.54 | 4.71 | 4.71 |
| 333.39 | 3.64 | 3.64 |
| 419.53 | 3.79 | 3.79 |
| 405.50 | 4.04 | 4.04 |
| 408.47 | 4.53 | 4.53 |