Basic Information
ID: ALA4328752
Type: Toxicity
Description: Toxicity in liver microsomes isolated from CYP activator dexamethasone-treated Sprague-Dawley rat assessed as induction of mitochondrial permeability transition by measuring mitochondrial swelling at 50 uM measured after 30 mins in absence of NADPH
Format: BAO_0000251
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4325877
Toxicity in liver microsomes isolated from CYP activator dexamethasone-treated Sprague-Dawley rat assessed as induction of mitochondrial permeability transition by measuring mitochondrial swelling at 50 uM measured after 30 mins in absence of NADPH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4328752
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 424.09 | 5.46 | 5.46 |
| 345.19 | 4.69 | 4.69 |
| 424.09 | 5.46 | 5.46 |
| 345.19 | 4.69 | 4.69 |
| 424.09 | 5.46 | 5.46 |
| 345.19 | 4.69 | 4.69 |
| 345.19 | 4.69 | 4.69 |