Basic Information
ID: ALA4328842
Type: Binding
Description: Inhibition of Influenza A virus (A/Puerto Rico/8/34(H1N1)) PA endonuclease infected in MDCK cells assessed as reduction in virus titer treated with cells for 1 hr prior to viral infection for 1 hr followed by compound washout and subsequent compound addition measured after 48 hrs by hemagglutination test
Organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Cell type: MDCK
Activity Charts
Bioactivity
Activity Types for Assay ALA4328842
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 179.31 | 2.55 | 2.55 |
| 426.52 | 4.24 | 4.24 |
| 402.45 | 4.50 | 4.50 |
| 504.44 | 5.05 | 5.05 |
| 366.47 | 4.22 | 4.22 |
| 368.44 | 3.01 | 3.01 |
| 368.44 | 3.01 | 3.01 |
| 370.42 | 1.80 | 1.80 |
| 435.36 | 5.53 | 5.53 |
| 290.37 | 2.30 | 2.30 |
| 320.40 | 2.31 | 2.31 |
| 308.36 | 2.44 | 2.44 |