Basic Information
ID: ALA4328868
Type: Binding
Description: Inhibition of Clostridium difficile toxin A transfected in CHO cells assessed as reduction in caspase 3/7 activation pre-incubated for 1 hr before TcdA addition by luminescence based assay
Organism: Clostridioides difficile
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4328868
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.87 | 3.64 | 3.64 |
| 543.99 | 5.04 | 5.04 |
| 556.02 | 4.91 | 4.91 |
| 561.43 | 4.94 | 4.94 |
| 510.98 | 4.88 | 4.88 |
| 541.01 | 4.60 | 4.60 |
| 561.43 | 4.94 | 4.94 |
| 535.99 | 5.05 | 5.05 |
| 540.02 | 5.20 | 5.20 |
| 536.98 | 4.21 | 4.21 |
| 593.99 | 5.92 | 5.92 |
| 559.99 | 4.74 | 4.74 |
| 499.96 | 3.91 | 3.91 |
| 550.02 | 5.06 | 5.06 |
| 470.31 | 4.29 | 4.29 |
| 557.01 | 4.30 | 4.30 |
| 556.02 | 4.91 | 4.91 |
| 572.02 | 4.61 | 4.61 |
| 564.40 | 5.38 | 5.38 |
| 576.44 | 5.25 | 5.25 |
| 535.99 | 4.82 | 4.82 |
| 510.98 | 4.88 | 4.88 |
| 577.43 | 4.65 | 4.65 |
| 551.01 | 4.77 | 4.77 |
| 510.98 | 4.88 | 4.88 |
| 496.95 | 4.57 | 4.57 |
| 614.41 | 6.26 | 6.26 |
| 499.96 | 3.91 | 3.91 |
| 571.42 | 5.11 | 5.11 |
| 560.44 | 5.55 | 5.55 |
| 504.76 | 4.95 | 4.95 |
| 609.99 | 5.62 | 5.62 |
| 577.43 | 4.65 | 4.65 |