Assay Report Card

Basic Information

ID: ALA4329009

Type: Binding

Description: Inhibition of Tdp1 in human MCF7 cells assessed as potentiation of topotecan-induced antiproliferative activity by measuring increase in maximal inhibition above aditivity at 1 uM after 3 days by [3H]-thymidine incorporation assay

Organism: Homo sapiens

Cell type: MCF7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
582.435.265.26