Basic Information
ID: ALA4329060
Type: Binding
Description: Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by fluorescence-based Amplex Red MAO assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Monoamine oxidase B(ALA2039)
Document: ALA4325892
Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by fluorescence-based Amplex Red MAO assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4329060
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 171.24 | 1.90 | 1.90 |
| 302.35 | 2.37 | 2.37 |
| 289.46 | 4.63 | 4.63 |
| 331.54 | 5.66 | 5.66 |
| 317.52 | 5.41 | 5.41 |
| 331.54 | 5.80 | 5.80 |
| 373.63 | 6.83 | 6.83 |
| 317.52 | 5.27 | 5.27 |
| 345.57 | 6.19 | 6.19 |
| 359.60 | 6.58 | 6.58 |
| 373.63 | 6.97 | 6.97 |
| 331.54 | 5.66 | 5.66 |
| 303.49 | 5.02 | 5.02 |
| 359.60 | 6.44 | 6.44 |
| 317.52 | 5.41 | 5.41 |
| 331.54 | 5.80 | 5.80 |
| 373.63 | 6.83 | 6.83 |
| 345.57 | 6.05 | 6.05 |
| 345.57 | 6.05 | 6.05 |
| 359.60 | 6.44 | 6.44 |
| 317.52 | 5.27 | 5.27 |
| 359.60 | 6.58 | 6.58 |
| 345.57 | 6.19 | 6.19 |
| 303.49 | 5.02 | 5.02 |
| 317.52 | 5.41 | 5.41 |
| 303.49 | 4.88 | 4.88 |
| 303.49 | 5.02 | 5.02 |
| 317.52 | 5.12 | 5.12 |
| 317.52 | 5.27 | 5.27 |
| 303.49 | 4.88 | 4.88 |
| 275.44 | 4.24 | 4.24 |