Basic Information
ID: ALA4329618
Type: Binding
Description: Inhibition of human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 residues) T790M mutant expressed in baculovirus expression system after 1 hr in presence of ULight-labeled peptide substrate and ATP by LANCE ultra kinase assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA4325914
Inhibition of human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 residues) T790M mutant expressed in baculovirus expression system after 1 hr in presence of ULight-labeled peptide substrate and ATP by LANCE ultra kinase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4329618
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.07 | 6.14 | 6.14 |
| 446.91 | 4.28 | 4.28 |
| 533.45 | 3.55 | 3.55 |
| 595.12 | 5.02 | 5.02 |
| 638.19 | 4.61 | 4.61 |
| 532.06 | 3.03 | 3.03 |
| 533.45 | 3.55 | 3.55 |
| 489.00 | 3.44 | 3.44 |