Basic Information
ID: ALA4329667
Type: Binding
Description: Inhibition of IKKbeta in human CD14-positive monocytes assessed as reduction in LPS-stimulated TNFalpha secretion preincubated for 30 mins followed by LPS stimulation and measured after 24 hrs by Alpha screen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4329667
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.53 | 3.46 | 3.46 |
| 494.66 | 3.93 | 3.93 |
| 426.54 | 2.40 | 2.40 |
| 510.66 | 3.17 | 3.17 |
| 454.60 | 3.00 | 3.00 |
| 496.68 | 4.17 | 4.17 |
| 386.45 | 3.37 | 3.37 |
| 414.50 | 4.14 | 4.14 |
| 396.51 | 4.00 | 4.00 |
| 368.46 | 3.23 | 3.23 |