Basic Information
ID: ALA4329828
Type: Binding
Description: Inhibition of P-gp-mediated doxorubicin efflux in human Lucena 1 cells assessed as ratio of doxorubicin fluorescence intensity in presence of compound to doxorubicin fluorescence intensity in absence of compound at 3.12 uM preincubated for 1 hr followed by doxorubicin addition measured after 1 hr by flow cytometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4329828
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 371.52 | 6.00 | 6.00 |
| 1202.63 | ||
| 440.54 | 5.30 | 5.30 |
| 468.59 | 6.08 | 6.08 |
| 496.64 | 6.86 | 6.86 |
| 356.46 | 4.16 | 4.16 |
| 384.52 | 4.94 | 4.94 |
| 412.57 | 5.72 | 5.72 |