Assay Report Card

Basic Information

ID: ALA4329992

Type: Binding

Description: Inhibition of recombinant human OGA expressed in Escherichia coli BL21 (DE3) at 20 uM using 4-Mu-GlcNAc as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
552.050.750.75
547.630.100.10
600.741.081.08
538.020.360.36
552.050.750.75
566.081.141.14
600.741.081.08
586.710.690.69
548.57-0.39-0.39
574.700.550.55
576.630.390.39
561.660.490.49
547.630.100.10
562.600.000.00
596.500.850.85
596.500.850.85
582.470.460.46
614.761.471.47
560.670.160.16
610.531.251.25
560.670.160.16
533.60-0.29-0.29
562.600.000.00
546.65-0.23-0.23