Assay Report Card

Basic Information

ID: ALA4330039

Type: ADME

Description: Inhibition of human ABHD12 expressed in HEK293 cells assessed as residual activity at 10 uM preincubated for 30 mins followed by 1-AG substrate addition and measured after 90 to 120 mins by fluorometric assay relative to control

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
539.525.555.55
397.586.126.12
396.605.745.74
369.575.945.94
383.566.036.03
397.595.015.01
553.555.855.85
469.656.296.29
567.586.346.34
397.586.346.34
412.605.705.70
508.138.448.44
383.606.246.24
382.575.435.43
384.595.525.52
508.138.448.44
411.616.436.43
427.615.485.48
422.595.995.99
473.687.787.78