Basic Information
ID: ALA4330684
Type: Binding
Description: Inhibition of voltage-dependent L-type calcium channel in human SH-SY5Y cells assessed as reduction in KCl-stimulated calcium influx at 10 uM preincubated for 30 mins in presence of Mag-Fura-2/AM dye followed by KCl stimulation and measured over 35 secs by fluorescence assay (Rvb =100%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: Voltage-gated L-type calcium channel(ALA2095229)
Document: ALA4330068
Inhibition of voltage-dependent L-type calcium channel in human SH-SY5Y cells assessed as reduction in KCl-stimulated calcium influx at 10 uM preincubated for 30 mins in presence of Mag-Fura-2/AM dye followed by KCl stimulation and measured over 35 secs by fluorescence assay (Rvb =100%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4330684
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.38 | 3.15 | 3.15 |
| 265.36 | 2.26 | 2.26 |
| 213.28 | 0.69 | 0.69 |
| 213.28 | 0.38 | 0.38 |
| 536.67 | 3.83 | 3.83 |
| 313.83 | 3.00 | 3.00 |
| 294.40 | 1.41 | 1.41 |
| 376.50 | 2.00 | 2.00 |
| 280.37 | 1.53 | 1.53 |
| 322.41 | 2.34 | 2.34 |
| 332.45 | 1.98 | 1.98 |
| 332.45 | 1.67 | 1.67 |
| 336.44 | 2.22 | 2.22 |
| 374.48 | 2.48 | 2.48 |
| 338.45 | 1.73 | 1.73 |
| 280.37 | 1.84 | 1.84 |