Basic Information
ID: ALA4331198
Type: Binding
Description: Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in insect cells using RtGWWRFYTLRRARQGNTKQR as substrate measured after 180 mins in presence of [gamma33P]ATP by topcount method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4331198
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.45 | 2.45 | 2.45 |
| 327.39 | 2.46 | 2.46 |
| 232.29 | 1.86 | 1.86 |
| 295.35 | 2.61 | 2.61 |
| 327.39 | 2.39 | 2.39 |
| 297.37 | 2.45 | 2.45 |
| 381.44 | 2.41 | 2.41 |
| 381.44 | 2.41 | 2.41 |
| 328.38 | 2.42 | 2.42 |
| 364.33 | 3.02 | 3.02 |
| 326.40 | 2.51 | 2.51 |
| 233.27 | 1.82 | 1.82 |
| 284.37 | 2.74 | 2.74 |
| 326.40 | 2.51 | 2.51 |
| 285.31 | 1.91 | 1.91 |
| 357.41 | 2.15 | 2.15 |