Assay Report Card

Basic Information

ID: ALA4331406

Type: ADME

Description: Drug metabolism in rat liver microsomes assessed as cytochrome P450-mediated N-demethylated metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis

Organism: Rattus norvegicus

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
316.353.493.49
309.374.664.66
262.364.254.25
348.456.256.25