Basic Information
ID: ALA4331523
Type: Binding
Description: Inhibition of human recombinant N-terminal GST-tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) using DHO as substrate preincubated for 5 mins followed by substrate addition and measured for 5 mins by DCPI dye-based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4331523
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.31 | 3.33 | 3.33 |
| 235.27 | 1.17 | 1.17 |
| 321.38 | 2.69 | 2.69 |
| 276.29 | 1.88 | 1.88 |
| 247.25 | 0.80 | 0.80 |
| 261.28 | 1.46 | 1.46 |
| 248.24 | 1.40 | 1.40 |
| 316.24 | 2.42 | 2.42 |
| 309.33 | 2.34 | 2.34 |
| 264.31 | 2.12 | 2.12 |
| 247.25 | 1.44 | 1.44 |
| 325.39 | 2.81 | 2.81 |
| 335.41 | 3.00 | 3.00 |
| 316.24 | 2.42 | 2.42 |
| 276.29 | 2.10 | 2.10 |
| 338.36 | 3.28 | 3.28 |
| 302.33 | 2.49 | 2.49 |