Basic Information
ID: ALA4331647
Type: Binding
Description: Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate addition and measured every min for 8 to 15 mins by FRET assay
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA4331647
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 559.75 | 5.18 | 5.18 |
| 602.78 | 3.63 | 3.63 |
| 674.88 | 4.65 | 4.65 |
| 573.78 | 5.49 | 5.49 |
| 750.83 | 7.26 | 7.26 |
| 577.74 | 5.32 | 5.32 |
| 686.94 | 6.45 | 6.45 |
| 630.83 | 4.41 | 4.41 |
| 646.83 | 3.34 | 3.34 |
| 654.77 | 5.59 | 5.59 |
| 670.94 | 6.67 | 6.67 |
| 545.72 | 4.70 | 4.70 |
| 648.85 | 5.84 | 5.84 |
| 614.83 | 5.39 | 5.39 |
| 628.86 | 5.69 | 5.69 |
| 644.86 | 5.07 | 5.07 |
| 658.88 | 5.46 | 5.46 |
| 571.64 | 4.60 | 4.60 |
| 584.76 | 5.06 | 5.06 |
| 630.83 | 4.41 | 4.41 |
| 654.90 | 6.22 | 6.22 |
| 629.85 | 4.20 | 4.20 |
| 594.20 | 5.84 | 5.84 |
| 616.80 | 4.29 | 4.29 |
| 612.82 | 5.05 | 5.05 |
| 586.78 | 4.61 | 4.61 |
| 616.80 | 4.02 | 4.02 |
| 627.75 | 6.20 | 6.20 |