Basic Information
ID: ALA4332034
Type: Binding
Description: Inhibition of ERK5 in human SN12C cells transduced with MEF2-responsive transcription element assessed as reduction in MEF2 transcription by measuring luciferase signal after 16 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SN12C
Target: Mitogen-activated protein kinase 7(ALA5332)
Document: ALA4330097
Inhibition of ERK5 in human SN12C cells transduced with MEF2-responsive transcription element assessed as reduction in MEF2 transcription by measuring luciferase signal after 16 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4332034
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.45 | 3.54 | 3.54 |
| 487.48 | 3.78 | 3.78 |
| 432.40 | 3.95 | 3.95 |
| 415.42 | 4.86 | 4.86 |
| 459.42 | 4.48 | 4.48 |
| 515.54 | 3.28 | 3.28 |
| 407.47 | 3.68 | 3.68 |
| 476.46 | 3.90 | 3.90 |
| 430.43 | 5.16 | 5.16 |
| 431.41 | 4.56 | 4.56 |
| 462.43 | 3.51 | 3.51 |
| 391.47 | 3.98 | 3.98 |
| 529.57 | 3.59 | 3.59 |
| 430.43 | 5.16 | 5.16 |
| 432.40 | 3.95 | 3.95 |
| 421.50 | 4.07 | 4.07 |
| 431.41 | 4.56 | 4.56 |
| 462.43 | 3.96 | 3.96 |
| 464.57 | 3.61 | 3.61 |
| 446.43 | 4.14 | 4.14 |
| 415.42 | 4.86 | 4.86 |
| 455.54 | 3.07 | 3.07 |
| 462.43 | 3.96 | 3.96 |
| 415.42 | 4.86 | 4.86 |
| 501.51 | 3.90 | 3.90 |
| 461.44 | 4.57 | 4.57 |
| 648.79 | 3.16 | 3.16 |
| 514.55 | 4.08 | 4.08 |
| 446.43 | 4.14 | 4.14 |
| 435.52 | 4.45 | 4.45 |
| 500.53 | 3.70 | 3.70 |
| 432.40 | 3.95 | 3.95 |
| 395.43 | 3.81 | 3.81 |
| 445.44 | 4.69 | 4.69 |
| 447.46 | 4.93 | 4.93 |
| 433.55 | 4.96 | 4.96 |
| 437.50 | 3.04 | 3.04 |
| 415.42 | 4.86 | 4.86 |
| 461.44 | 4.57 | 4.57 |
| 461.44 | 4.57 | 4.57 |