Assay Report Card

Basic Information

ID: ALA4332191

Type: Functional

Description: In vivo antagonist activity at PPAR receptor in C57Bl/6 mouse assessed as reduction in CPT1a gene expression at 30 mg/kg, po administered twice daily for 3 consecutive days and subsequent single dosing on day 4 following fasting from day 2 to 4 during compound dosing and measured at 4 hrs post last dose by Qiazol/RNeasy staining based assay

Organism: Mus musculus

Strain: C57Bl/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
619.627.057.05