Basic Information
ID: ALA4332212
Type: Functional
Description: Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha-induced calcium flux by Fluo-4 NW or Calcium 4 dye based FLIPR TETRA assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4332212
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.48 | 3.00 | 3.00 |
| 403.41 | 3.88 | 3.88 |
| 420.39 | 4.85 | 4.85 |
| 425.45 | 2.29 | 2.29 |
| 424.46 | 2.89 | 2.89 |
| 414.36 | 4.51 | 4.51 |
| 413.37 | 5.11 | 5.11 |
| 413.37 | 5.11 | 5.11 |
| 414.36 | 4.51 | 4.51 |
| 414.36 | 4.51 | 4.51 |
| 413.37 | 5.11 | 5.11 |
| 425.45 | 2.29 | 2.29 |
| 451.48 | 2.78 | 2.78 |
| 453.50 | 3.24 | 3.24 |
| 346.37 | 3.49 | 3.49 |
| 395.38 | 4.97 | 4.97 |
| 375.40 | 4.10 | 4.10 |
| 453.50 | 3.02 | 3.02 |
| 453.50 | 3.24 | 3.24 |
| 466.54 | 3.78 | 3.78 |
| 439.47 | 2.68 | 2.68 |
| 423.47 | 3.50 | 3.50 |
| 424.46 | 2.89 | 2.89 |
| 451.48 | 2.82 | 2.82 |
| 465.51 | 3.17 | 3.17 |
| 389.39 | 3.79 | 3.79 |
| 439.47 | 2.40 | 2.40 |
| 438.48 | 3.00 | 3.00 |
| 467.53 | 3.63 | 3.63 |
| 424.46 | 2.89 | 2.89 |
| 452.51 | 3.34 | 3.34 |
| 409.41 | 5.03 | 5.03 |
| 333.31 | 3.52 | 3.52 |
| 492.45 | 3.91 | 3.91 |
| 346.37 | 3.49 | 3.49 |
| 425.45 | 2.29 | 2.29 |
| 346.37 | 3.49 | 3.49 |
| 425.41 | 4.98 | 4.98 |
| 402.43 | 3.45 | 3.45 |
| 452.51 | 3.39 | 3.39 |
| 413.37 | 5.11 | 5.11 |
| 464.27 | 6.28 | 6.28 |
| 423.47 | 3.50 | 3.50 |
| 439.47 | 2.85 | 2.85 |
| 415.35 | 3.90 | 3.90 |
| 452.51 | 3.34 | 3.34 |
| 379.82 | 4.75 | 4.75 |
| 466.54 | 3.78 | 3.78 |
| 507.59 | 3.03 | 3.03 |
| 429.83 | 5.63 | 5.63 |