Basic Information
ID: ALA4332913
Type: Functional
Description: In vivo antagonist activity at MOR in Swiss Webster mouse assessed reduction in morphine-induced antinociceptive effect by measuring morphine MPE at 10 mg/kg, sc preincubated for 5 mins followed by morphine addition and measured after 20 min post morphine challenge by tail immersion test relative to control
Format: BAO_0000218
Organism: Mus musculus
Strain: Swiss Webster
Target: Mus musculus(ALA375)
Document: ALA4330119
In vivo antagonist activity at MOR in Swiss Webster mouse assessed reduction in morphine-induced antinociceptive effect by measuring morphine MPE at 10 mg/kg, sc preincubated for 5 mins followed by morphine addition and measured after 20 min post morphine challenge by tail immersion test relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4332913
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 503.64 | 3.35 | 3.35 |
| 515.53 | 3.17 | 3.17 |
| 523.63 | 3.82 | 3.82 |
| 543.71 | 4.59 | 4.59 |
| 492.53 | 2.06 | 2.06 |
| 465.53 | 2.29 | 2.29 |
| 472.55 | 2.02 | 2.02 |
| 491.54 | 1.85 | 1.85 |
| 529.68 | 4.20 | 4.20 |
| 475.59 | 2.71 | 2.71 |
| 515.65 | 3.81 | 3.81 |
| 505.57 | 1.94 | 1.94 |