Basic Information
ID: ALA4332969
Type: Binding
Description: Inhibition of human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in baculovirus expression system in presence of 1 mM ATP by HTRF assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK3(ALA2148)
Document: ALA4330124
Inhibition of human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in baculovirus expression system in presence of 1 mM ATP by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4332969
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 526.52 | 3.17 | 3.17 |
| 285.35 | 1.94 | 1.94 |
| 494.47 | 3.59 | 3.59 |
| 561.36 | 3.80 | 3.80 |
| 512.46 | 3.73 | 3.73 |
| 512.46 | 3.73 | 3.73 |
| 508.50 | 4.02 | 4.02 |
| 440.50 | 2.88 | 2.88 |
| 471.47 | 2.48 | 2.48 |
| 482.46 | 3.49 | 3.49 |
| 489.88 | 3.76 | 3.76 |
| 508.50 | 3.90 | 3.90 |
| 494.47 | 3.59 | 3.59 |
| 510.52 | 4.27 | 4.27 |
| 508.50 | 3.60 | 3.60 |
| 516.91 | 3.64 | 3.64 |
| 508.50 | 4.02 | 4.02 |
| 456.50 | 2.58 | 2.58 |
| 508.50 | 3.98 | 3.98 |
| 473.49 | 2.77 | 2.77 |
| 460.92 | 3.22 | 3.22 |
| 469.46 | 1.93 | 1.93 |
| 551.53 | 2.70 | 2.70 |
| 551.57 | 3.52 | 3.52 |
| 495.46 | 2.98 | 2.98 |
| 364.41 | 1.30 | 1.30 |
| 508.50 | 4.34 | 4.34 |
| 444.47 | 2.71 | 2.71 |
| 473.49 | 2.70 | 2.70 |
| 492.46 | 3.04 | 3.04 |
| 508.50 | 3.98 | 3.98 |
| 496.49 | 3.81 | 3.81 |
| 426.48 | 2.57 | 2.57 |
| 496.49 | 3.88 | 3.88 |