Inhibition of JAK1/TYK2 in human PBMC assessed as reduction in IFNalpha-induced STAT1 phosphorylation at 10 uM preincubated for 2 hrs followed by IFNa...

Basic Information

ID: ALA4332987

Type: Binding

Description: Inhibition of JAK1/TYK2 in human PBMC assessed as reduction in IFNalpha-induced STAT1 phosphorylation at 10 uM preincubated for 2 hrs followed by IFNalpha stimulation measured after 30 mins by Western blot

Format: BAO_0000223

Organism: Homo sapiens

Target: JAK1/TYK2(ALA3301391)

Document: ALA4330124

Inhibition of JAK1/TYK2 in human PBMC assessed as reduction in IFNalpha-induced STAT1 phosphorylation at 10 uM preincubated for 2 hrs followed by IFNalpha stimulation measured after 30 mins by Western blot: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4332987

Inhibition

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
312.38	1.54	1.54
471.47	2.48	2.48

Parent Molecular Weight

ALogP

Polar Surface Area

312.38

1.54

471.47

2.48

Inhibition of JAK1/TYK2 in human PBMC assessed as reduction in IFNalpha-induced STAT1 phosphorylation at 10 uM preincubated for 2 hrs followed by IFNa...

Basic Information

Activity Charts

Compound Summary