Basic Information
ID: ALA4332987
Type: Binding
Description: Inhibition of JAK1/TYK2 in human PBMC assessed as reduction in IFNalpha-induced STAT1 phosphorylation at 10 uM preincubated for 2 hrs followed by IFNalpha stimulation measured after 30 mins by Western blot
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4332987
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 471.47 | 2.48 | 2.48 |