Basic Information
ID: ALA4333011
Type: Binding
Description: Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS-TEV-PARylated-PARP1 (2 to 1014 residues) as substrate measured after 10 mins by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4333011
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.49 | 0.80 | 0.80 |
| 403.46 | 0.31 | 0.31 |
| 435.48 | 0.75 | 0.75 |
| 537.52 | 1.10 | 1.10 |
| 421.45 | 0.26 | 0.26 |
| 519.53 | 0.80 | 0.80 |
| 486.57 | 0.56 | 0.56 |
| 501.54 | 0.51 | 0.51 |
| 483.55 | 0.56 | 0.56 |
| 436.47 | 1.31 | 1.31 |