Basic Information
ID: ALA4333012
Type: Binding
Description: Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured after 30 to 120 mins by Alexafluor 488-conjugated secondary antibody and Hoechst 33342 staining based assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4333012
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.49 | 0.80 | 0.80 |
| 403.46 | 0.31 | 0.31 |
| 435.48 | 0.75 | 0.75 |
| 537.52 | 1.10 | 1.10 |
| 421.45 | 0.26 | 0.26 |
| 519.53 | 0.80 | 0.80 |
| 486.57 | 0.56 | 0.56 |
| 501.54 | 0.51 | 0.51 |
| 483.55 | 0.56 | 0.56 |
| 436.47 | 1.31 | 1.31 |