Inhibition of CYP2C9 in human liver microsomes assessed as reduction in tolbutamide 4-hydroxylation by tandem mass spectrometry analysis

Basic Information

ID: ALA4333060

Type: ADME

Description: Inhibition of CYP2C9 in human liver microsomes assessed as reduction in tolbutamide 4-hydroxylation by tandem mass spectrometry analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 2C9(ALA3397)

Document:  ALA4330127

Inhibition of CYP2C9 in human liver microsomes assessed as reduction in tolbutamide 4-hydroxylation by tandem mass spectrometry analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
393.873.253.25