Basic Information
ID: ALA4333204
Type: Binding
Description: Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged Cul3 (unknown origin) expressed in baculovirus infected Sf9 insect cells measured after 1 hr by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Unchecked(ALA612545)
Document: ALA4330129
Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged Cul3 (unknown origin) expressed in baculovirus infected Sf9 insect cells measured after 1 hr by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4333204
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 157.24 | 1.85 | 1.85 |
| 177.29 | 1.25 | 1.25 |
| 205.35 | 2.03 | 2.03 |
| 239.37 | 2.68 | 2.68 |
| 163.27 | 0.86 | 0.86 |
| 340.49 | 0.34 | 0.34 |
| 253.39 | 2.99 | 2.99 |
| 394.63 | 3.15 | 3.15 |
| 310.55 | 2.14 | 2.14 |
| 395.04 | 2.37 | 2.37 |
| 424.59 | 3.02 | 3.02 |
| 408.53 | 1.50 | 1.50 |
| 467.66 | 3.99 | 3.99 |
| 250.39 | 0.85 | 0.85 |
| 235.31 | 1.69 | 1.69 |
| 345.45 | 3.16 | 3.16 |
| 381.57 | 2.69 | 2.69 |
| 240.37 | 2.57 | 2.57 |
| 293.35 | 2.42 | 2.42 |
| 263.37 | 2.37 | 2.37 |
| 394.61 | 2.97 | 2.97 |
| 354.56 | 2.28 | 2.28 |
| 188.32 | 1.14 | 1.14 |
| 278.40 | 0.76 | 0.76 |
| 234.35 | 0.76 | 0.76 |
| 390.45 | 0.95 | 0.95 |
| 372.60 | 2.71 | 2.71 |
| 404.60 | 2.70 | 2.70 |
| 448.79 | 2.52 | 2.52 |
| 298.80 | 3.45 | 3.45 |
| 482.67 | 4.10 | 4.10 |
| 510.68 | 4.32 | 4.32 |
| 301.37 | 2.63 | 2.63 |
| 264.35 | 2.80 | 2.80 |
| 373.54 | 3.71 | 3.71 |
| 248.42 | 1.57 | 1.57 |
| 225.27 | 1.29 | 1.29 |
| 430.04 | 4.05 | 4.05 |
| 322.52 | 1.12 | 1.12 |
| 191.28 | 0.52 | 0.52 |
| 220.32 | -0.18 | -0.18 |
| 241.36 | 2.11 | 2.11 |
| 172.25 | 1.01 | 1.01 |
| 396.58 | 2.79 | 2.79 |
| 523.75 | 5.21 | 5.21 |
| 404.01 | 2.34 | 2.34 |
| 253.33 | 0.28 | 0.28 |
| 366.51 | 2.15 | 2.15 |
| 518.71 | 4.54 | 4.54 |
| 172.25 | 1.01 | 1.01 |
| 467.66 | 3.99 | 3.99 |
| 292.43 | 0.62 | 0.62 |
| 381.57 | 2.69 | 2.69 |
| 451.66 | 3.07 | 3.07 |
| 395.59 | 3.39 | 3.39 |
| 371.62 | 3.17 | 3.17 |
| 235.31 | 1.69 | 1.69 |
| 216.31 | 2.82 | 2.82 |
| 191.32 | 1.64 | 1.64 |
| 248.37 | 0.75 | 0.75 |
| 306.41 | 0.30 | 0.30 |
| 255.36 | 2.34 | 2.34 |
| 381.57 | 3.26 | 3.26 |
| 250.32 | 2.41 | 2.41 |
| 234.39 | 1.18 | 1.18 |
| 352.48 | 1.65 | 1.65 |
| 248.35 | 2.58 | 2.58 |
| 264.42 | 1.24 | 1.24 |
| 322.41 | -0.04 | -0.04 |
| 432.62 | 3.23 | 3.23 |
| 354.52 | 0.43 | 0.43 |
| 516.13 | 5.35 | 5.35 |
| 262.40 | 1.10 | 1.10 |
| 387.60 | 2.34 | 2.34 |
| 458.69 | 4.02 | 4.02 |
| 480.70 | 4.27 | 4.27 |
| 256.35 | 1.74 | 1.74 |
| 250.33 | 2.09 | 2.09 |
| 187.27 | 0.80 | 0.80 |
| 385.64 | 3.56 | 3.56 |
| 366.51 | 2.04 | 2.04 |
| 438.62 | 3.06 | 3.06 |
| 269.46 | 1.14 | 1.14 |
| 265.34 | 2.19 | 2.19 |
| 240.35 | 2.07 | 2.07 |
| 590.88 | 5.62 | 5.62 |
| 232.30 | 1.24 | 1.24 |
| 524.71 | 4.37 | 4.37 |
| 186.28 | 1.35 | 1.35 |
| 437.66 | 3.90 | 3.90 |
| 484.62 | -1.37 | -1.37 |
| 250.33 | 2.09 | 2.09 |
| 269.39 | 2.65 | 2.65 |
| 254.40 | 2.96 | 2.96 |
| 264.37 | 0.42 | 0.42 |
| 346.50 | 2.86 | 2.86 |
| 240.35 | 2.07 | 2.07 |
| 262.38 | 2.62 | 2.62 |
| 220.32 | 0.37 | 0.37 |
| 308.54 | 1.85 | 1.85 |