Basic Information
ID: ALA4333229
Type: Binding
Description: Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4333229
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.32 | 3.96 | 3.96 |
| 414.44 | 4.61 | 4.61 |
| 382.46 | 4.38 | 4.38 |
| 412.45 | 4.47 | 4.47 |
| 363.44 | 3.49 | 3.49 |
| 465.31 | 4.74 | 4.74 |
| 363.44 | 3.67 | 3.67 |
| 337.42 | 4.11 | 4.11 |
| 347.44 | 3.51 | 3.51 |
| 360.22 | 3.80 | 3.80 |
| 415.87 | 3.85 | 3.85 |
| 396.49 | 4.69 | 4.69 |
| 446.30 | 3.61 | 3.61 |
| 361.81 | 3.99 | 3.99 |
| 355.39 | 3.86 | 3.86 |
| 539.22 | 4.72 | 4.72 |
| 526.42 | 6.07 | 6.07 |
| 457.36 | 4.60 | 4.60 |
| 363.44 | 3.67 | 3.67 |
| 474.35 | 4.35 | 4.35 |
| 363.39 | 2.45 | 2.45 |
| 416.91 | 5.04 | 5.04 |
| 417.45 | 1.86 | 1.86 |
| 355.76 | 2.54 | 2.54 |
| 363.44 | 3.67 | 3.67 |