Basic Information
ID: ALA4333723
Type: Binding
Description: Inhibition of kinase tracer 236 binding to recombinant full length His-tagged human CDK8/CycC expressed in baculovirus expression system at 10 uM preincubated for 20 mins followed by tracer addition and measured after 2 hrs by FRET-based LanthaScreen Eu kinase binding assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK8/Cyclin C(ALA3038474)
Document: ALA4330136
Inhibition of kinase tracer 236 binding to recombinant full length His-tagged human CDK8/CycC expressed in baculovirus expression system at 10 uM preincubated for 20 mins followed by tracer addition and measured after 2 hrs by FRET-based LanthaScreen Eu kinase binding assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4333723
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.35 | 4.35 |
| 343.45 | 4.92 | 4.92 |
| 387.39 | 1.08 | 1.08 |
| 340.81 | 3.90 | 3.90 |
| 364.42 | 4.60 | 4.60 |
| 416.89 | 4.97 | 4.97 |
| 362.39 | 3.86 | 3.86 |
| 340.77 | 4.05 | 4.05 |
| 370.45 | 5.04 | 5.04 |
| 418.54 | 3.51 | 3.51 |
| 402.90 | 5.25 | 5.25 |
| 366.81 | 4.51 | 4.51 |
| 377.45 | 1.16 | 1.16 |
| 386.90 | 5.55 | 5.55 |
| 302.34 | 3.85 | 3.85 |
| 347.44 | 4.98 | 4.98 |
| 400.36 | 4.66 | 4.66 |
| 348.40 | 4.32 | 4.32 |
| 421.89 | 3.72 | 3.72 |
| 400.48 | 4.24 | 4.24 |
| 423.86 | 3.17 | 3.17 |
| 410.54 | 5.69 | 5.69 |
| 418.54 | 3.51 | 3.51 |
| 427.93 | 4.84 | 4.84 |
| 385.22 | 4.16 | 4.16 |
| 368.82 | 4.88 | 4.88 |
| 324.77 | 4.35 | 4.35 |
| 389.42 | 2.58 | 2.58 |
| 380.88 | 5.12 | 5.12 |
| 405.46 | 4.41 | 4.41 |
| 367.45 | 5.19 | 5.19 |
| 364.42 | 4.60 | 4.60 |
| 392.42 | 3.87 | 3.87 |
| 362.39 | 3.86 | 3.86 |