Basic Information
ID: ALA4333772
Type: ADME
Description: Inhibition of human Nav1.5 at -50 mV holding potential by cell-based IonWorks barracuda automated electrophysiology method
Format: BAO_0000219
Organism: Homo sapiens
Target: Sodium channel protein type V alpha subunit(ALA1980)
Document: ALA4330138
Inhibition of human Nav1.5 at -50 mV holding potential by cell-based IonWorks barracuda automated electrophysiology method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4333772
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.48 | 3.68 | 3.68 |
| 461.58 | 3.51 | 3.51 |
| 413.54 | 2.46 | 2.46 |
| 332.43 | 2.67 | 2.67 |
| 412.56 | 3.94 | 3.94 |
| 360.44 | 2.20 | 2.20 |
| 360.48 | 3.45 | 3.45 |
| 376.48 | 2.82 | 2.82 |
| 358.46 | 3.45 | 3.45 |
| 361.47 | 1.87 | 1.87 |
| 360.48 | 3.30 | 3.30 |
| 416.59 | 4.72 | 4.72 |
| 359.45 | 1.78 | 1.78 |
| 360.48 | 3.30 | 3.30 |
| 334.44 | 2.70 | 2.70 |
| 461.58 | 3.51 | 3.51 |
| 378.47 | 3.59 | 3.59 |
| 361.47 | 1.87 | 1.87 |
| 292.36 | 1.71 | 1.71 |
| 376.52 | 3.94 | 3.94 |
| 375.49 | 2.21 | 2.21 |
| 388.53 | 4.08 | 4.08 |
| 459.57 | 3.42 | 3.42 |
| 278.33 | 1.40 | 1.40 |
| 374.51 | 3.84 | 3.84 |