Basic Information
ID: ALA4334280
Type: Functional
Description: Positive allosteric modulation of human mGluR3 expressed in HEK293 cells assessed as increase in glutamate-induced calcium mobilization preincubated for 10 mins followed by glutamate addition and measured for 3 mins by Fluo4-AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4334280
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 345.38 | 4.02 | 4.02 |
| 349.37 | 3.54 | 3.54 |
| 345.38 | 4.02 | 4.02 |
| 375.40 | 4.03 | 4.03 |
| 378.41 | 3.43 | 3.43 |
| 347.39 | 4.14 | 4.14 |
| 352.37 | 2.94 | 2.94 |
| 332.41 | 3.53 | 3.53 |