Basic Information
ID: ALA4334314
Type: Binding
Description: Inhibition of recombinant human C-terminal His/N-terminal FLAG-tagged TET2 (1129 to 2002 residues) expressed in baculovirus infected sf9 cells assessed as reduction in oxidation of methylated dsDNA at 100 uM after 2 hrs by chemiluminescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Methylcytosine dioxygenase TET2(ALA4523344)
Document: ALA4330181
Inhibition of recombinant human C-terminal His/N-terminal FLAG-tagged TET2 (1129 to 2002 residues) expressed in baculovirus infected sf9 cells assessed as reduction in oxidation of methylated dsDNA at 100 uM after 2 hrs by chemiluminescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4334314
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 297.75 | 3.14 | 3.14 |
| 255.20 | 1.83 | 1.83 |
| 297.75 | 3.14 | 3.14 |
| 297.75 | 3.14 | 3.14 |
| 187.20 | 0.81 | 0.81 |
| 221.65 | 1.47 | 1.47 |