Basic Information
ID: ALA4334353
Type: Binding
Description: Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection after 48 hrs by Bright-Glo luciferase assay
Format: BAO_0000019
Organism: Human immunodeficiency virus 1
Target: Human immunodeficiency virus type 1 reverse transcriptase(ALA247)
Document: ALA4330184
Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection after 48 hrs by Bright-Glo luciferase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4334353
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 2.65 | 2.65 |
| 343.81 | 4.73 | 4.73 |
| 371.86 | 5.35 | 5.35 |
| 359.88 | 5.45 | 5.45 |
| 387.93 | 6.07 | 6.07 |
| 330.35 | 3.55 | 3.55 |
| 282.34 | 3.76 | 3.76 |
| 280.29 | 2.41 | 2.41 |
| 313.74 | 3.67 | 3.67 |
| 328.76 | 4.80 | 4.80 |
| 289.72 | 3.19 | 3.19 |
| 299.72 | 3.18 | 3.18 |
| 304.35 | 4.30 | 4.30 |
| 254.29 | 3.14 | 3.14 |
| 327.77 | 4.06 | 4.06 |
| 286.76 | 3.98 | 3.98 |
| 304.31 | 2.89 | 2.89 |
| 280.29 | 2.41 | 2.41 |