Basic Information
ID: ALA4334555
Type: Binding
Description: Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4334555
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 335.41 | 2.80 | 2.80 |
| 314.34 | 1.37 | 1.37 |
| 431.49 | 3.79 | 3.79 |
| 459.55 | 4.40 | 4.40 |
| 459.55 | 3.77 | 3.77 |
| 474.56 | 3.22 | 3.22 |
| 474.56 | 3.85 | 3.85 |
| 445.52 | 3.46 | 3.46 |
| 461.52 | 3.16 | 3.16 |
| 491.54 | 3.17 | 3.17 |
| 431.49 | 3.15 | 3.15 |
| 488.59 | 3.53 | 3.53 |
| 509.01 | 3.87 | 3.87 |