Basic Information
ID: ALA4334738
Type: Binding
Description: Inhibition of His6-tagged NOTUM purified from human HEK293S cells using OPTS as substrate incubated for 1 hr by fluorescence based assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Palmitoleoyl-protein carboxylesterase NOTUM(ALA3714531)
Document: ALA4334426
Inhibition of His6-tagged NOTUM purified from human HEK293S cells using OPTS as substrate incubated for 1 hr by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4334738
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 295.34 | 2.90 | 2.90 |
| 262.70 | 2.75 | 2.75 |
| 281.36 | 2.96 | 2.96 |
| 256.31 | 2.80 | 2.80 |
| 292.34 | 3.56 | 3.56 |
| 240.31 | 2.96 | 2.96 |
| 282.30 | 2.28 | 2.28 |
| 292.34 | 3.56 | 3.56 |
| 296.25 | 3.12 | 3.12 |
| 295.34 | 2.90 | 2.90 |
| 296.33 | 2.29 | 2.29 |
| 294.35 | 3.50 | 3.50 |
| 309.37 | 3.38 | 3.38 |
| 258.35 | 3.12 | 3.12 |
| 241.29 | 3.01 | 3.01 |
| 256.31 | 2.43 | 2.43 |
| 246.24 | 2.24 | 2.24 |
| 312.76 | 3.91 | 3.91 |
| 292.34 | 3.56 | 3.56 |
| 253.26 | 1.97 | 1.97 |
| 255.32 | 2.46 | 2.46 |
| 262.70 | 2.75 | 2.75 |
| 293.33 | 2.96 | 2.96 |
| 308.39 | 2.96 | 2.96 |
| 295.34 | 2.90 | 2.90 |
| 295.34 | 2.90 | 2.90 |
| 228.25 | 2.10 | 2.10 |
| 242.28 | 2.41 | 2.41 |
| 292.34 | 3.56 | 3.56 |
| 257.29 | 2.11 | 2.11 |
| 258.28 | 2.11 | 2.11 |
| 296.33 | 2.29 | 2.29 |
| 292.34 | 3.56 | 3.56 |
| 292.34 | 3.56 | 3.56 |
| 312.76 | 3.91 | 3.91 |
| 295.34 | 2.90 | 2.90 |
| 243.27 | 1.80 | 1.80 |
| 323.40 | 3.94 | 3.94 |
| 293.33 | 2.96 | 2.96 |
| 292.34 | 3.56 | 3.56 |
| 241.29 | 2.44 | 2.44 |
| 256.31 | 2.09 | 2.09 |
| 280.33 | 3.49 | 3.49 |
| 256.31 | 2.72 | 2.72 |
| 309.37 | 3.38 | 3.38 |
| 280.33 | 3.49 | 3.49 |
| 260.27 | 2.55 | 2.55 |
| 292.34 | 3.56 | 3.56 |
| 245.28 | 1.75 | 1.75 |