Basic Information
ID: ALA4334742
Type: Binding
Description: Inhibition of NOTUM in human HEK293S cells harbouring TCF/LEF luciferase reporter gene assessed as activation wnt signalling pathway at 10 uM incubated for 10 mins followed by wnt-3A addition further incubated for 1 hr by steady-glo luciferase assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Palmitoleoyl-protein carboxylesterase NOTUM(ALA3714531)
Document: ALA4334426
Inhibition of NOTUM in human HEK293S cells harbouring TCF/LEF luciferase reporter gene assessed as activation wnt signalling pathway at 10 uM incubated for 10 mins followed by wnt-3A addition further incubated for 1 hr by steady-glo luciferase assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4334742
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.34 | 3.56 | 3.56 |
| 293.33 | 2.96 | 2.96 |