Basic Information
ID: ALA4334744
Type: Binding
Description: Inhibition of NOTUM in human HEK293S cells harbouring TCF/LEF luciferase reporter gene assessed as activation wnt signalling pathway incubated for 10 mins followed by wnt-3A addition further incubated for 1 hr by steady-glo luciferase assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Palmitoleoyl-protein carboxylesterase NOTUM(ALA3714531)
Document: ALA4334426
Inhibition of NOTUM in human HEK293S cells harbouring TCF/LEF luciferase reporter gene assessed as activation wnt signalling pathway incubated for 10 mins followed by wnt-3A addition further incubated for 1 hr by steady-glo luciferase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4334744
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.79 | 3.40 | 3.40 |
| 309.37 | 3.38 | 3.38 |
| 323.40 | 3.94 | 3.94 |