Basic Information
ID: ALA4334834
Type: Binding
Description: Inhibition of 20S immunoproteasome beta 5 chymotrypsin-like activity in human THP-1 cell lysates using Suc-LLVY-AMC as substrate preincubated for 30 mins followed by substrate addition and measured for 90 mins by fluorescence based assay
Format: BAO_0000220
Organism: Homo sapiens
Cell type: THP-1
Subcellular Fraction: Lysate
Target: Proteasome subunit beta type-8(ALA5620)
Document: ALA4334435
Inhibition of 20S immunoproteasome beta 5 chymotrypsin-like activity in human THP-1 cell lysates using Suc-LLVY-AMC as substrate preincubated for 30 mins followed by substrate addition and measured for 90 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4334834
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.43 | 4.97 | 4.97 |
| 405.43 | 5.15 | 5.15 |