Basic Information
ID: ALA4334844
Type: Binding
Description: Time-dependent inhibition of human immunoproteasome beta 5i subunit assessed as increase in IC50 value using Suc-LLVY-AMC as substrate co-incubated with substrate without preincubation by fluorescence based analysis relative to 30 mins preincubated compound-treated control
Format: BAO_0000357
Organism: Homo sapiens
Target: Proteasome subunit beta type-8(ALA5620)
Document: ALA4334435
Time-dependent inhibition of human immunoproteasome beta 5i subunit assessed as increase in IC50 value using Suc-LLVY-AMC as substrate co-incubated with substrate without preincubation by fluorescence based analysis relative to 30 mins preincubated compound-treated control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4334844
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 4.65 | 4.65 |
| 383.43 | 4.97 | 4.97 |
| 405.43 | 5.15 | 5.15 |