Basic Information
ID: ALA4334854
Type: ADME
Description: Inhibition of human constitutive proteasome beta 2 subunit using Boc-LRR-AMC as substrate preincubated for 30 mins followed by substrate addition measured for 120 mins by fluorescence based assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Proteasome Macropain subunit(ALA3492)
Document: ALA4334435
Inhibition of human constitutive proteasome beta 2 subunit using Boc-LRR-AMC as substrate preincubated for 30 mins followed by substrate addition measured for 120 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4334854
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 4.65 | 4.65 |
| 383.43 | 4.97 | 4.97 |
| 407.40 | 4.60 | 4.60 |
| 407.40 | 4.60 | 4.60 |
| 395.37 | 4.73 | 4.73 |
| 369.40 | 4.58 | 4.58 |
| 405.43 | 5.15 | 5.15 |
| 355.37 | 4.19 | 4.19 |
| 456.27 | 5.35 | 5.35 |
| 391.40 | 4.90 | 4.90 |