Basic Information
ID: ALA4334911
Type: Binding
Description: Inhibition of human GSK-3alpha S449A mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by scintillation counting method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4334911
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 512.55 | 3.42 | 3.42 |
| 338.32 | 2.07 | 2.07 |
| 473.10 | 3.73 | 3.73 |
| 446.50 | 1.61 | 1.61 |
| 386.39 | 0.91 | 0.91 |
| 489.92 | 5.40 | 5.40 |
| 438.53 | 3.33 | 3.33 |
| 402.41 | 3.69 | 3.69 |
| 315.31 | 2.78 | 2.78 |
| 323.33 | 1.73 | 1.73 |
| 325.32 | 2.07 | 2.07 |
| 285.28 | 2.42 | 2.42 |
| 339.20 | 3.60 | 3.60 |
| 356.36 | 2.75 | 2.75 |
| 355.38 | 2.38 | 2.38 |
| 356.36 | 2.75 | 2.75 |
| 270.31 | 3.17 | 3.17 |
| 387.37 | 2.97 | 2.97 |
| 404.88 | 3.90 | 3.90 |
| 339.20 | 4.39 | 4.39 |
| 341.37 | 3.39 | 3.39 |
| 367.21 | 3.17 | 3.17 |
| 357.37 | 4.13 | 4.13 |
| 476.27 | 3.46 | 3.46 |
| 390.85 | 3.51 | 3.51 |
| 314.32 | 1.99 | 1.99 |
| 315.31 | 2.99 | 2.99 |
| 304.76 | 2.95 | 2.95 |
| 318.76 | 3.65 | 3.65 |
| 349.76 | 3.65 | 3.65 |
| 360.82 | 4.01 | 4.01 |
| 278.27 | -0.32 | -0.32 |
| 345.34 | 3.00 | 3.00 |
| 349.76 | 3.65 | 3.65 |
| 464.58 | 3.66 | 3.66 |
| 208.23 | -0.74 | -0.74 |
| 425.52 | 4.78 | 4.78 |
| 363.24 | 3.36 | 3.36 |
| 329.34 | 3.30 | 3.30 |
| 345.34 | 3.00 | 3.00 |
| 348.33 | 3.33 | 3.33 |
| 279.32 | 2.42 | 2.42 |
| 303.33 | 2.48 | 2.48 |
| 349.76 | 3.65 | 3.65 |
| 447.25 | 3.18 | 3.18 |
| 314.37 | 1.03 | 1.03 |
| 318.79 | 4.05 | 4.05 |
| 318.79 | 3.25 | 3.25 |
| 288.74 | 3.64 | 3.64 |
| 453.30 | 3.23 | 3.23 |
| 314.32 | 1.99 | 1.99 |
| 370.46 | 0.07 | 0.07 |
| 441.40 | 3.33 | 3.33 |
| 346.84 | 4.07 | 4.07 |
| 349.76 | 2.85 | 2.85 |
| 343.36 | 3.61 | 3.61 |
| 304.76 | 3.74 | 3.74 |
| 384.37 | 2.61 | 2.61 |
| 346.41 | 4.84 | 4.84 |
| 332.81 | 3.63 | 3.63 |
| 370.43 | 3.45 | 3.45 |
| 440.46 | -1.77 | -1.77 |
| 367.26 | 4.33 | 4.33 |
| 304.76 | 3.74 | 3.74 |
| 329.34 | 3.30 | 3.30 |
| 315.31 | 2.20 | 2.20 |
| 388.83 | 3.29 | 3.29 |
| 418.52 | 2.15 | 2.15 |
| 314.32 | 2.78 | 2.78 |
| 280.33 | 3.44 | 3.44 |
| 400.87 | 4.75 | 4.75 |
| 354.44 | 1.57 | 1.57 |
| 390.42 | 4.54 | 4.54 |
| 269.30 | 3.29 | 3.29 |
| 412.92 | 5.98 | 5.98 |
| 408.91 | 6.11 | 6.11 |
| 336.83 | 3.43 | 3.43 |
| 360.44 | 4.71 | 4.71 |
| 339.20 | 4.39 | 4.39 |
| 394.88 | 5.80 | 5.80 |