Basic Information
ID: ALA4334914
Type: ADME
Description: Inhibition of human GSK-3beta H350L mutant (2 to end residues) at 10 uM using phospho GS2 peptide as substrate after 40 mins by [gamma-33ATP] radiometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4334914
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 512.55 | 3.42 | 3.42 |
| 473.10 | 3.73 | 3.73 |
| 315.31 | 2.78 | 2.78 |
| 325.32 | 2.07 | 2.07 |
| 285.28 | 2.42 | 2.42 |
| 339.20 | 3.60 | 3.60 |
| 356.36 | 2.75 | 2.75 |
| 356.36 | 2.75 | 2.75 |
| 270.31 | 3.17 | 3.17 |
| 387.37 | 2.97 | 2.97 |
| 404.88 | 3.90 | 3.90 |
| 339.20 | 4.39 | 4.39 |
| 390.85 | 3.51 | 3.51 |
| 314.32 | 1.99 | 1.99 |
| 315.31 | 2.99 | 2.99 |
| 304.76 | 2.95 | 2.95 |
| 349.76 | 3.65 | 3.65 |
| 360.82 | 4.01 | 4.01 |
| 345.34 | 3.00 | 3.00 |
| 349.76 | 3.65 | 3.65 |
| 363.24 | 3.36 | 3.36 |
| 329.34 | 3.30 | 3.30 |
| 345.34 | 3.00 | 3.00 |
| 348.33 | 3.33 | 3.33 |
| 349.76 | 3.65 | 3.65 |
| 318.79 | 4.05 | 4.05 |
| 318.79 | 3.25 | 3.25 |
| 314.32 | 1.99 | 1.99 |
| 346.84 | 4.07 | 4.07 |
| 349.76 | 2.85 | 2.85 |
| 343.36 | 3.61 | 3.61 |
| 304.76 | 3.74 | 3.74 |
| 346.41 | 4.84 | 4.84 |
| 332.81 | 3.63 | 3.63 |
| 370.43 | 3.45 | 3.45 |
| 367.26 | 4.33 | 4.33 |
| 304.76 | 3.74 | 3.74 |
| 329.34 | 3.30 | 3.30 |
| 315.31 | 2.20 | 2.20 |
| 388.83 | 3.29 | 3.29 |
| 314.32 | 2.78 | 2.78 |
| 390.42 | 4.54 | 4.54 |
| 412.92 | 5.98 | 5.98 |
| 408.91 | 6.11 | 6.11 |
| 336.83 | 3.43 | 3.43 |
| 360.44 | 4.71 | 4.71 |
| 339.20 | 4.39 | 4.39 |
| 394.88 | 5.80 | 5.80 |