Assay Report Card

Basic Information

ID: ALA4335358

Type: Binding

Description: Inhibition of recombinant full-length human PI3K p110alpha E545K mutant/p85alpha assessed as residual activity at 1 uM assessed as residual activity at 1 uM using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
315.312.992.99
388.833.293.29