Basic Information
ID: ALA4335358
Type: Binding
Description: Inhibition of recombinant full-length human PI3K p110alpha E545K mutant/p85alpha assessed as residual activity at 1 uM assessed as residual activity at 1 uM using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay relative to control
Format: BAO_0000223
Organism: Homo sapiens
Target: PI3-kinase p110-alpha/p85-alpha(ALA2111367)
Document: ALA4334438
Inhibition of recombinant full-length human PI3K p110alpha E545K mutant/p85alpha assessed as residual activity at 1 uM assessed as residual activity at 1 uM using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4335358
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.31 | 2.99 | 2.99 |
| 388.83 | 3.29 | 3.29 |