Basic Information
ID: ALA4335367
Type: Functional
Description: Antiviral activity against EGFP-fused HCV JFH-1 harboring K78E/E2-G451R/NS3-M260K/NS5A-T462I mutant infected in human Huh7.5.1 cells assessed as reduction in viral RNA level after 2 days by qRT-PCR analysis
Organism: Hepacivirus hominis
Strain: JFH-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4335367
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.40 | 6.13 | 6.13 |
| 443.46 | 6.85 | 6.85 |
| 446.50 | 6.56 | 6.56 |
| 409.41 | 5.83 | 5.83 |
| 488.51 | 6.21 | 6.21 |
| 432.47 | 6.17 | 6.17 |
| 443.47 | 6.85 | 6.85 |
| 396.46 | 3.74 | 3.74 |
| 463.43 | 7.19 | 7.19 |
| 399.51 | 6.53 | 6.53 |
| 428.51 | 5.07 | 5.07 |
| 434.49 | 6.42 | 6.42 |
| 474.48 | 6.16 | 6.16 |
| 426.54 | 6.22 | 6.22 |
| 373.43 | 5.24 | 5.24 |
| 540.61 | 8.08 | 8.08 |
| 429.44 | 6.92 | 6.92 |
| 469.45 | 7.89 | 7.89 |
| 441.42 | 6.17 | 6.17 |
| 368.45 | 4.36 | 4.36 |
| 420.46 | 6.03 | 6.03 |
| 406.43 | 5.64 | 5.64 |
| 475.46 | 5.53 | 5.53 |
| 443.46 | 6.85 | 6.85 |
| 443.47 | 6.85 | 6.85 |
| 377.85 | 5.89 | 5.89 |
| 459.46 | 6.83 | 6.83 |
| 406.43 | 6.01 | 6.01 |
| 526.59 | 7.37 | 7.37 |
| 455.45 | 6.00 | 6.00 |
| 441.42 | 5.83 | 5.83 |
| 447.49 | 4.98 | 4.98 |
| 448.51 | 6.81 | 6.81 |
| 486.49 | 6.18 | 6.18 |
| 380.46 | 4.51 | 4.51 |
| 459.46 | 5.86 | 5.86 |