Basic Information
ID: ALA4335386
Type: Functional
Description: Antiviral activity against EGFP-fused HCV JFH-1 harboring K78E/E2-G451R/NS3-M260K/NS5A-T462I mutant infected in human Huh7.5.1 cells assessed as inhibition of viral entry at 0.01 uM preincubated for 2 hrs at 4 degC followed by virus/compound mixture wash-out and subsequent compound addition and measured up to 10 hrs at 37 degC
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Huh7.5.1
Target: Huh7.5.1(ALA4483247)
Document: ALA4334439
Antiviral activity against EGFP-fused HCV JFH-1 harboring K78E/E2-G451R/NS3-M260K/NS5A-T462I mutant infected in human Huh7.5.1 cells assessed as inhibition of viral entry at 0.01 uM preincubated for 2 hrs at 4 degC followed by virus/compound mixture wash-out and subsequent compound addition and measured up to 10 hrs at 37 degC: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4335386
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.49 | 6.42 | 6.42 |